Product ID:CEFUROXIME SODIUM
MSDS Date:11/12/1990
FSC:6505
NIIN:01-209-1205
MSDS Number: BWMHG

Emergency Phone: 919-248-2100/2700

Info Phone: 919-248-2354

Preparer: DIRECTOR, ENVIRON SAFETY

Cage: 34006

Telephone: 919-248-2100

Cage: 34006

CEFUROXIME SODIUM

CAS: 56238-63-2

RTECS: XI0330000

Fraction By Weight: 100%

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ZINACEF IS A CEPHALOSPORIN ANTIBIOTIC
USED TO TREAT BACTERIAL INGECTIONS DUE TO SUSCEPTIBLE ORGANISMS.
ACUTE DUST EXPOSURE MAY CAUSE MILD TO SEVERE ALLERGIC REACTIONS IN
SENSITIVE INDIVIDUALS. THERE I S NO RECORDED FATAL ANAPHYLAXIS, BUT
ITIS A POSSIBILITY. MAY BE A SKIN SENSITIZER.
Explanation of Carcinogenicity:THERE IS NO PUBLISHED EVIDENCE THAT THE
COMPOUND IS CARCINOGENIC OR TERATOGENIC. WAS NEGATIVE ON THE
MUTAGENIC AMES TEST
Effects of Overexposure:INHALED:RESPIRATORY IRRITATION,ITCHY SKIN
RASHES,HIVES,RUNNY/STUFFY NOSE,CHEST TIGHTNESS,SWELLING & DIFFICULT
BREATHING. SKIN:SENSITIZER. RED ITCHY SKIN RASH AFTER REPEATED
CONTACT.
Medical Cond Aggravated by Exposure:ALLERGIC REACTIONS MAY OCCUR IN
INDIVIDUALS SENSITIVE TO CEPHALOSPORINS, PENICILLLINS OR RELATED
COMPOUNDS.

First Aid:EYE:FLUSH THOROUGHLY W/LARGE AMOUNT OF WATER. GET MEDICAL
ATTENTION. SKIN:REMOVE CONTAMINATED CLOTHING & WASH W/SOAP & WATER.
INHALED:REMOVE VICTIM TO FRESH AIR. IF BREATHING IS DIFFICULT OR
CEASES, G IVE OXYGEN OR CPR. GET MEDICAL ATTENTION. INGESTED:RINSE
MOUTH WITH WATER. GET MEDICAL ATTENTION.

Extinguishing Media:WATER SPRAY, FOAM, MULTI-PURPOSE DRY CHEMICAL.
Fire Fighting Procedures:WEAR FULL PROTECTIVE CLOTHING AND USE SELF
CONTAINED BREATHING APPARATUS.
Unusual Fire/Explosion Hazard:AS WITH ANY ORGANIC DUST, THERE IS
POTENTIAL FOR EXPLOSION WHEN SUSPENDED IN AIR IN HIGH
CONCENTRATIONS.

Spill Release Procedures:WEAR FULL PROTECTIVE EQUIPMENT. AVOID BODY
CONTACT AND/OR BREATHING DUST. COLLECT SPILLAGE BY CAREFULLLY
SWEEPING OR VACUUMING WITH HEPA FILTEREDVACUUM & PLACE IN LABELED,
SEALED CONTAINER FOR REUSE O R DISPOSAL. WASH AREA AFTER VACUUMING.
Neutralizing Agent:MFR GAVE NO INFORMATION ON MSDS.

Handling and Storage Precautions:USE STORAGE PRACTICES THAT WILL
MINIMIZE GENERATION OF DUST.
Other Precautions:SPECIAL CARE SHOULD BE TAKEN TO INSURE THAT
CONTAMINATED CLOTHING & EQUIPMENT ARE PROPERLY CLEANED AFTER USE.

Respiratory Protection:WEAR RESPIRATORY PROTECTIVE EQUIPMENT WHEN
EXPOSED TO DUST LEVELS THAT EXCEED THE ESTIMATED SAGE WORKING LEVEL
(MFR'S). FOLLOW NIOSH, ANSI Z88.2, AND THE RESPIRATORY EQUIPMENT
MANUFACTURER'S RECOMMEND ATIONS.
Ventilation:PROVIDE LOCAL EXHAUST VENTILATION SYSTEM AT THE SOURCE OF
DUST GENERATION.
Protective Gloves:WEAR PROTECTIVE GLOVES AT ALL TIMES.
Eye Protection:PROTECT EYE FROM DUST.
Other Protective Equipment:A PROTECTIVE OUTER GARMENT IS ADEQUATE FOR
LOW DUST EXPOSURE. FOR HIGH EXPOSURE, WEAR WEAR FULL BODY
PROTECTION.
Work Hygienic Practices:ALL SKIN CONTACT SHOULD BE AVOIDED. EMPLOYEES
EXPOSED TO DUST SHOULD CHANGE CLOTHES & SHOWER AT END OF WORK
ASSIGNMENT.
Supplemental Safety and Health
NONE

HCC:N1
NRC/State Lic Num:NONE
Melt/Freeze Pt:M.P/F.P Text:420F,216C
Solubility in Water:15% W/V
Appearance and Odor:WHITE TO CREAMY WHITE POWDER, ODOR NOT LISTED

Stability Indicator/Materials to Avoid:YES
NO KNOWN INCOMPATIBILITIES.
Stability Condition to Avoid:SLIGHTLY UNSTABLE IN AIR & WILL SLOWLY
DECOMPOSE. THE MATERIAL SHOULD BE PROTECTED FROM LIGHT AND STORED
UNDER NITROGEN.
Hazardous Decomposition Products:THERMAL DECOMPOSITION PRODUCTS INCLUDE
TOXIC & CORROSIVE OXIDES OF NITROGEN AND SULFUR.

Waste Disposal Methods:INCINERATE AT AN APPROVED FACILITY I/A/W
FEDERAL, STATE & LOCAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.